A new women's version of the legendary running shoe—originally intended to be the greatest in the world—is the MADE in USA 990v6. The V6's top has pigskin and synthetic overlays that cover the mesh underlay from heel to toe, giving it a quick-drying and streamlined appearance. This is among the most significant modifications the 990 has ever experienced.

Still, internal changes are the most significant. The addition of FuelCell midsole cushioning allows for a tangible and noticeable progression of the 990. There is no conventional midfoot in the new design, which is a big performance improvement. The size range for women is smaller than that of males.